Rink Amide Resin
4-(2', 4'-Dimethoxyphenyl-Fmoc-aminomethyl)-phenoxymethyl resin
Amide rink resin is an excellent support for the Fmoc SPPS of peptide amides. This resin is more acid sensitive than Rink Amide-AM and Rink Amide-MBHA resins. Cleavage with high concentrations of TFA can lead to the breakdown of the linker, with the concomitant formation of by-products that can not be removed by simple washes. These problems appear to be minimized through the use of low TFA concentrations or by the addition of trialkylsilanes to the cleavage mixture.
Product No.
|
Particle size(mesh)
|
Loading(mmol/g resin)
|
LXSS07-1-1201
|
100-200; 200-400
|
0.3-0.6
|
LXSS07-1-1202
|
100-200; 200-400
|
0.6-0.8
|
LXSS07-1-1203
|
100-200; 200-400
|
0.8-1.0
|
Comments
Post a Comment