Sieber Resin

9-Fmoc-Aminoxanthen-3-yloxy-polystyrene resin
A hyper acid-labile linker or the Fmoc SPPS of protected amides via mild 1% TFA cleavage. The sieber amide resin can be readily reductively alkylated to provide a support suited to the synthesis of secondary carboxamides. This resin has also been employed to produce protected peptide fragments in wich the C-terminal carboxylic acid group is blocked as a hydroxymethylphenoxy-β-alaninamide ester.

Product No
Particle size(mesh)
Loading(mmol/g resin)
LXSS10-1-1401
100-200; 200-400
0.2-0.4
LXSS10-1-1402
100-200; 200-400
0.4-0.6
LXSS10-1-1403
100-200; 200-400
0.6-0.8

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